Police said they received a report of a vehicle driving on the wrong side of the road on Mount Hamilton shortly after 10 a.m. Tuesday. City patrol officers were instructed to look after the vehicle through a broadcast of all cars issued after receiving the report.
Twenty minutes later, police said a pedestrian was hit by the vehicle while parked in Park Avenue South on Markland Street, just south of downtown.
The 78-year-old man was taken to hospital with serious injuries where he was later pronounced dead.
It is the seventh pedestrian death of the city of the year.
Police claim that the driver fled after the accident. They were arrested a short distance from Elmwood Avenue near Garth Street.
In a press release, police said three police officers and the driver were injured during the arrest and taken to hospital.
The Ontario Special Investigation Unit has been called in to investigate the incident.
No other details have been given by the police.