It happened in the area of ​​Ontario and Shuter streets at 8:14 p.m.  There, emergency crews located a man who suffered multiple stab wounds to his trunk, police said.
The victim, who was identified by investigators on Tuesday as 58-year-old Abdi Jama, was rushed to a trauma center where he was pronounced dead.
He is the 18th homicide victim of the city of the year.
Toronto Police Insp.  Roger Caracciolo told CP24 on stage Sunday that Jama met another man on Ontario Street shortly before he got into a fight when he was stabbed.
Shamar James, 30, of Toronto, was charged with second-degree murder in connection with the incident.  He appeared in a Toronto courtroom Monday.
Police ask anyone with information about their investigation to contact them at 416-808-7400 or Crime Stoppers.