Emergency crews were called to 10 Glen Everest Road, east of Kingston Road, before noon for a stabbing.
When they arrived, officers located a man in the lobby of a building suffering from apparent trauma.
He was rushed to the hospital, where he later died.  On Sunday, police identified the man as 38-year-old Leon Tyrell of Toronto.  He is the city’s 43rd homicide victim.
Police have issued an arrest warrant for the suspect, 34-year-old Sathiskumar “Ryan” Rajaratnam.  He is wanted for second degree murder.
The suspect is described as six-foot-6, 180 pounds, with a slim build, side-shaven dark hair and brown eyes.  He has tattoos on his chest and shoulders.
Police said Rajaratnam is believed to be armed, violent and dangerous, advising anyone who spots him to stay away and call 911 immediately.
Investigators are urging anyone with information about the stabbing to contact them at 416-808-7400 or Crime Stoppers anonymously at 416-222-TIPS (8477).